4Ts Score (HIT)aaIPI (Age-adjusted IPI)ABC Score (Massive Transfusion)Absolute Neutrophil Count Age-adjusted D-dimer Threshold aGvHD Grading (Glucksberg/MAGIC)AL Amyloidosis Staging (Mayo)Anti-Xa Monitoring Interpreter Antiphospholipid Syndrome Classification Binet / Rai Staging (CML)Blood Volume Calculator Caprini VTE Risk Score CISNE Score CLL-IPI Coombs-Negative Haemolysis Checklist Corrected Reticulocyte Count CRS Grading (ASTCT 2019)DAT Interpretation Algorithm Deauville Score Interpreter DIC Score (ISTH)DIPSS (MF)DIPSS-Plus (MF)DOAC Dose Selector DOAC Renal Dose Adjustment DRI (Disease Risk Index)Durie-Salmon Staging (historical)EBMT Risk Score ELN 2022 AML Risk Classification ELTS Score (CML)England & Fraser Index EUTOS Score (CML)Expected Hb Rise Calculator (Post-Transfusion)Factor Inhibitor Bethesda Titre Interpreter Febrile Neutropaenia Risk (MASCC)Fibrinogen Replacement FLIPI (Follicular Lymphoma IPI)FLIPI-2 French TTP Score GAPSS (Global APS Score)Haemophilia Severity Classification HbS Percentage Target Calculator HCT-CI (Comorbidity Index)HEP Score Heparin Nomogram (Weight-based)Hepatic Iron Index HERDOO2 Rule HFE Haemochromatosis Risk Estimator ICANS Grading (ASTCT 2019)IMWG Response Criteria (Myeloma)IPI (International Prognostic Index)IPSID / Lugano Classification IPSS-M (Molecular IPSS)IPSS-R (Revised IPSS for MDS)Iron Deficit Calculator (Ganzoni Formula)ISS (Myeloma)ISTH Bleeding Assessment Tool (BAT)ISTH Non-Overt DIC Score ITP Bleeding Score IWG ITP Response Criteria JAK2V617F Allele Burden Interpreter Karnofsky Performance Scale Leucostasis Risk Threshold Lupus Anticoagulant (LAC) Reporting Framework MAGIC aGvHD Biomarker Score MCV-based Anaemia Algorithm Mentzer Index MIPI (MCL IPI)MIPSS70+ v2.0 (MF)Mixing Study Interpretation MRD Assessment Threshold Interpreter mSMART 3.0 (Myeloma)MTP Activation Criteria NCCN-IPI NIH Chronic GvHD Scoring NTDT Iron Burden Estimator Padua RAM PBT (Paediatric BAT)PCNSL MSKCC Score PERC Rule Perioperative Anticoagulation Bridging PESI Score (PE Mortality)PLASMIC Score Platelet Increment Calculator (CCI)PNH Clone Size Interpreter R-IPI (Revised IPI)R-ISS (Revised ISS)Reticulocyte Index (RPI)Revised Geneva Score (PE)Revised Response Criteria (NHL)Revised Zubrod / ECOG Performance Shine & Lal Index Sickle Cell Disease Risk (TCD)SLiM-CRAB Criteria SOKAL Score (CML)Sokal/EUTOS/ELTS Comparison sPESI (Simplified PESI)TACO Risk Score Thalassaemia Transfusion Threshold Thrombocytopaenia Differential Thrombophilia Screening Eligibility Algorithm Time in Therapeutic Range (TTR)TLS Risk Classification Transferrin Saturation Calculator Vienna Prediction Model von Willebrand Factor Activity Interpreter Warfarin Dose Calculator Wells Score (DVT)Wells Score (PE)WHO 2022 AML Classification Mapper WHO Bleeding Scale YEARS Algorithm

ELN 2022 AML Risk Classification

ELN 2022 Consensus: AML genetic risk classification. Select any cytogenetic or molecular abnormalities found at diagnosis. The highest risk category usually dictates the clinical recommendation.

Favorable Markers

Adverse Markers

Genetic/Molecular Factors Not Listed?

Classified as Intermediate Risk

Includes FLT3-ITD without favorable fusions and other mutations not elsewhere specified.

Guidelines & Evidence

Verified

Last Review: 2026

When to Use

When to Use

Prognostic stratification of adult patients with Acute Myeloid Leukemia (AML) at the time of diagnosis.

Determining the appropriateness of allogeneic stem cell transplantation in CR1.

Standardizing genetic risk assessment across clinical trials and center registrations.

Patient Population

Adult patients with newly diagnosed AML (excluding APL). Primarily validated in patients receiving intensive induction chemotherapy.

When Not to Rely on This Score Alone

Acute Promyelocytic Leukemia (APL / M3) — has separate risk and management protocols.

Pediatric AML — although genetic factors overlap, the prognostic significance of certain mutations (e.g., FLT3-ITD) differs in children.

Patients with significant comorbidities — ELN risk is biological; patient fitness must be assessed separately.

Last Comprehensive Review: 2026

Related Hematology Tools

NTDT Iron Burden Estimator

Durie-Salmon Staging

Perioperative Anticoagulation Bridging

French TTP Score

Warfarin Dose Calculator

IWG ITP Response Criteria

Platelet Increment Calculator

Hematology Calculators Internal Medicine Calculators Emergency Medicine Calculators

Have feedback about this calculator?Let us know.